RNaseq count

RNaseq count

Users can access the gene expression data from published studies for which the read count file was made available to the BGH. Metadata are provided to link with the original study and experiment design by defining all libraries.

These read count files are rarely published, and we encourage the community to share them with us to complete datasets.

Read count files can also be used to perform additional analyses with the DIANE instance set up on the BGH. It includes:

• Raw count data pre-processing and sample-wise normalization
• Customizable differential expression analysis
• Gene ontology enrichment analysis for model organisms
• Expression based clustering in the framework of Poisson Mixture Models, and characterization of those clusters with generalized linear models and GO enrichment analysis
• Machine learning based Gene regulatory network inference

The full documentation of the DIANE software can be found here